Product Description
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Information
ApplicationELISA, WB
Research AreaCancer, Neuroscience, Signal transduction
Species ReactivityHuman, Mouse, Rat
Host SpeciesRabbit
Immunogen / Amino acidsRecombinant protein of human MAPT
ClonalityPolyclone
IsotypeIgG
Specifications
FormLiquid
Storage BufferPBS with 0.05% sodium azide, 50% glycerol, pH7.3
Concentration0.3mg/ml
Recommended DilutionWB(1:200-1:1000)
Misc Information
Alternative NamesAI413597, AW045860, DDPAC, FLJ31424, FTDP 17, G protein beta1/gamma2 subunit interacting factor 1, MAPT, MAPTL, MGC134287, MGC138549, MGC156663, Microtubule associated protein tau, Microtubule associated protein tau isoform 4, Microtubule-associated protein tau, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, Paired helical filament tau, Paired helical filament-tau, PHF tau, PHF-tau, PPND, PPP1R103, Protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, TAU, TAU, Tauopathy and respiratory failure, included.