tcna1137 MRP1 Antibody / ABCC1

Data sheet

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Product Description

The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.

Information

ApplicationWB, FACS, IHC-P, IF
Species ReactivityHuman. Others not tested.
Host SpeciesMouse
Immunogen / Amino acidsHuman recombinant protein was used as the immunogen for this MRP1 antibody.
ConjugationUnconjugated
ClonalityMonoclonal
ClonesMRP1/1343
IsotypeMouse IgG1

Specifications

FormLiquid
Storage Buffer0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Recommended DilutionWestern blot: 0.5-1ug/ml
FACS: 0.5-1ug/10^6 cells
IF: 1-2ug/ml
IHC (FFPE): 1-2ug/ml for 30 min at RTThe concentration stated for each application is a general starting point. Variations in protocols
secondaries and substrates may require the MRP1 antibody to be titered up or down for optimal performance.

Misc Information

Storage InstructionStore the MRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
SwissProtP33527
Gene ID4363 (human);
ReferencesProtein G affinity chromatography
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