tcna1381 Mouse Anti-Human IgG Heavy Chain Antibody

Data sheet

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Product Description

Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It reacts with all sub-classes of gamma chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Information

ApplicationIHC-P
Species ReactivityHuman. Other species not known.
Host SpeciesMouse
Immunogen / Amino acidsHuman Ig Gamma Chain was used as the immunogen for this recombinant human IgG antibody.
ConjugationUnconjugated
ClonalityRecombinant Mouse Monoclonal
ClonesrIG266
IsotypeMouse IgG1, kappa

Specifications

FormLiquid
Storage Buffer0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Concentration0.2 mg/ml
Recommended DilutionImmunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT
Prediluted IHC only format : incubate for 30 min at RT (1)The optimal dilution of the recombinant human IgG antibody for each application should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required)
drip mAb solution onto the tissue section and incubate at RT for 30 min.

Misc Information

Storage InstructionStore the recombinant human IgG antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
SwissProtP01857
ReferencesProtein G affinity chromatography
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