tcba13660 GAPDH Mouse Monoclonal Ab (High Dilution)

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Product Description

This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.


Research AreaEpigenetics & Nuclear Signaling, Epigenetic Modifications, Epigenetic Modifications_Methylation, Epigenetics & Nuclear Signaling, Epigenetic Modifications, Epigenetic Modifications_Methylation,
Species ReactivityHuman, Mouse, Rat
Host SpeciesMouse
Immunogen / Amino acidsRecombinant protein of human GAPDH


Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Tested ApplicationWB, IHC, IF
Recommended DilutionWB 1:50000 - 1:200000
IHC 1:50 - 1:200
IF 1:50 - 1:200

Misc Information

Storage InstructionStore at -20℃. Avoid freeze / thaw cycles.
Alternative NamesG3PD; GAPD; HEL-S-162eP; GAPDH
Gene ID2597
Calculated Molecular Weight31kDa/36kDa
Observed Molecular Weight36kD
PurificationAffinity purification
NotesAntibody Dilution procedure: Put 5ul AC033 into 45 ul buffer(with 50% glycerol), diluted 1:10, 000 for using. The diluted antibody can be stored at -20℃ without aliquot.
Cellular LocationCytoplasm,Membrane,Nucleus,cytoskeleton,cytosol,perinuclear region,
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