Product Description
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.
Information
ApplicationWB, IHC, IF, IP
Research AreaCancer, Autophagy pathway, Cardiovascular, Cell Biology, Metabolism, NF-κB pathway, RNA Binding Protein(RBP),
Species ReactivityHuman, Mouse, Rat
Host SpeciesRabbit
IsotypeIgG
Specifications
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:20 - 1:50
Misc Information
Storage InstructionStore at -20℃. Avoid freeze / thaw cycles.
Alternative NamesDAP1;GMP1;OFC10;PIC1;SENP2;SMT3;SMT3C;SMT3H3;UBL1
Calculated Molecular Weight8kDa/11kDa
PurificationAffinity purification
Cellular LocationCell membrane,Cytoplasm,Nucleus,Nucleus membrane,Nucleus speckle,PML body,