tcba179 MCL1 Polyclonal Antibody

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Product Description

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Information

ApplicationWB, IHC, IF
Research AreaCancer, Apoptosis, Cell Biology, Metabolism,
Species ReactivityHuman, Mouse
Host SpeciesRabbit
IsotypeIgG

Specifications

FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended DilutionWB 1:500 - 1:2000
IHC 1:100 - 1:200
IF 1:50 - 1:200

Misc Information

Storage InstructionStore at -20℃. Avoid freeze / thaw cycles.
Alternative Namesbcl2-L-3;BCL2L3;EAT;Mcl-1;MCL1-ES;mcl1/EAT;MCL1L;MCL1S;TM
SwissProtQ07820
Gene ID4170 (human);
Calculated Molecular Weight28kDa/37kDa
PurificationAffinity purification
Cellular LocationCytoplasm,Membrane,Mitochondrion,Nucleus,Single-pass membrane protein,nucleoplasm,
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