tcsc3431 DGAT1-IN-1

DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM(cell lysate from Hep3B cells overexpressing human DGAT1).

IC50 value: < 10 nM

Target: DGAT1 inhibitor

Imidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparation

By Kim, Dooseop; Bok, Juhan; Shin, Sunmi

From PCT Int. Appl. (2013), WO 2013119040 A1 20130815.