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Product Description
ML277(CID53347902) is a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator with EC50 of 270 nM.
IC50 value: 270 nM (EC50) [1]
Target: K(v)7.1 activator
ML277 was shown to be highly selective against other KCNQ channels (>100-fold selectivity versus KCNQ2 and KCNQ4) as well as against the distantly related hERG potassium channel.
Information
CAS No1401242-74-7
FormulaC23H25N3O4S2
Clinical Informationclinicalinformation
PathwayMembrane Transporter/Ion Channel
TargetPotassium Channel
Specifications
Purity / Grade>98%
SolubilityDMSO : ≥ 56 mg/mL (118.75 mM)
Smilessmiles
Misc Information
Alternative NamesCID-53347902
Observed Molecular Weight471.59
related data
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