tcsc3260 GSK-J2

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Product Description

GSK-J2 is an isomer of GSK-J1 that does not have any specific activity. GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.

In Vitro: GSK-J2 is an isomer of GSK-J1, and shows poor activity towards KDM6A and KDM6B, with IC50 of > 100 μM and 49 μM, respectively[1].

Information

CAS No1394854-52-4
FormulaC22H23N5O2
Clinical Informationclinicalinformation
PathwayEpigenetics
TargetHistone Demethylase

Specifications

Purity / Grade>98%
SolubilityDMSO : ≥ 42 mg/mL (107.84 mM)
Smilessmiles

Misc Information

Observed Molecular Weight389.45
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