tcsc3238 B-Raf IN 1

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Product Description

B-Raf IN 1 is a potent and selective B-Raf kinase inhibitor with an IC50 of 24 nM.

In Vitro: B-Raf IN 1 (Compound 10n) inhibits WM 266-4 and HT29 cells with IC50s of 0.92 and 0.78 μM, respectively[1].

Information

CAS No950736-05-7
FormulaC29H24F3N5O
Clinical Informationclinicalinformation
PathwayMAPK/ERK Pathway
TargetRaf

Specifications

Purity / Grade>98%
SolubilityDMSO : ≥ 53 mg/mL (102.81 mM)
Smilessmiles

Misc Information

Observed Molecular Weight515.53
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