tcsc3222 BTS

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Product Description

BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility.

IC50 value: 5 uM

Target: Ca2+-stimulated myosin S1 ATPase

BTS also weakens myosin’s interaction with F-actin. BTS is much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II.

Information

CAS No1576-37-0
FormulaC14H15NO2S
Clinical Informationclinicalinformation
PathwayCytoskeleton
TargetMyosin

Specifications

Purity / Grade>98%
SolubilityH2O : < 0.1 mg/mL (insoluble); DMSO : ≥ 33.33 mg/mL (127.54 mM)
Smilessmiles

Misc Information

Alternative NamesN-Benzyl-p-toluenesulfonamide;N-Tosylbenzylamine
Observed Molecular Weight261.34
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