tcsc3181 Tolazoline

Tolazoline(NSC35110; Imidaline) is a non-selective competitive α-adrenergic receptor antagonist.

IC50 value:

Target: α-adrenoceptor antagonist

Tolazoline can be synthesized by the heterocyclation of the ethyl ester of iminophenzylacetic acid with ethylene diamine, which forms the desired product. The structure of tolazoline is strikingly similar to α-adrenergic agonists, which are antiedema sympathomimetics.