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BioChemicals
BIBF 1202
tcsc3025
BIBF 1202
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AVAILABLE SIZES
1mg
5mg
$
326.00
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ORDERING INFORMATION
International
TAICLONE BIOTECH CORP.
order@taiclone.com
+886-2-2735-9682
+886-2-2735-9807
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Product Description
BIBF 1202 is the carboxylate metabolite of BIBF 1120 which inhibits
VEGFR2
kinase with an
IC
50
of 62 nM.
IC50 & Target: IC50: 62 nM (VEGFR2)
[1]
In Vitro:
The major metabolic pathway for BIBF 1120 is methyl ester cleavage to BIBF 1202. Subsequently, the free carboxyl group of BIBF 1202 is glucuronidated to 1-O-acylglucuronide
[2]
.
Information
CAS No
894783-71-2
Formula
C
30
H
31
N
5
O
4
Clinical Information
clinicalinformation
Pathway
Protein Tyrosine Kinase/RTK
Target
VEGFR
Specifications
Purity / Grade
>98%
Solubility
DMSO : ≥ 45 mg/mL (85.62 mM)
Smiles
smiles
Misc Information
Observed Molecular Weight
525.6
related data
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