tcsc2939 Ceftibuten

Ceftibuten(Sch39720) is a third-generation cephalosporin antibiotic.

IC50:

Target: Antibacterial

Ceftibuten displayed high activity against Haemophilus influenzae and Branhamella catarrhalis. There was reduced activity against Streptococcus pneumoniae (MIC90 16 mg/l). The protein binding of Ceftibuten was 77% and the primary target site PBP 3. A high degree of stability to beta-lactamase hydrolysis was observed. [1]