tcsc2892 Brimonidine

Brimonidine (UK 14304) is a full α2-adrenergic receptor (α2-AR) agonist.

IC50 & Target: α2-adrenergic Receptor.

In Vitro: [3H]Brimonidine (UK 14304) is a full agonist at alpha 2-adrenergic receptors. [3H]Brimonidine (UK 14304) labels at least 2 specific binding sites in human brain that both have the characteristics of an alpha 2-adrenergic binding site. GTP decreases agonist binding at both of these sites, but with different potencies at each site [1-3].