tcsc2286 S186

S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA); a new strontium-specific chelating agent.

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In a case test for 4 person who took 90Sr in due to an internal contaminated accident, the APAP was adminstrated intramuscularly once a day for 3 days, the increase excretion of 90Sr was obvious and no side effects was observed among them. Recently, S186 has also been approved by Shanghai Municipal Health Bureau for emergency medical use in China.