tcsc1900 NBI-98854

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Product Description

NBI-98854 is a potent, highly selective, VMAT2 inhibitor that is effective in regulating the levels of dopamine release during nerve communication.

IC50 value:

Target: VMAT2

NBI-98854 completed a Phase I single ascending dose clinical trial in healthy male volunteers in Canada under an approved Clinical Trial Application with Health Canada.This trial showed NBI-98854 to be generally safe and well tolerated.

Information

CAS No171598-74-6
FormulaC19H29NO3
Clinical Informationclinicalinformation
PathwayMembrane Transporter/Ion Channel
TargetMonoamine Transporter

Specifications

Purity / Grade>98%
Solubility10 mM in DMSO
Smilessmiles

Misc Information

Alternative Names(2R, 3R, 11bR)-rel-Dihydrotetrabenazine;(2R, 3R, 11bR)-rel-DHTBZ
Observed Molecular Weight319.44
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