tcsc1562 DB07268

DB07268 is a potent and selective JNK1 inhibitor with an IC₅₀ value of 9 nM.

IC50 & Target: IC50: 9 nM (JNK1), 0.82 μM (CHK1), 5.5 μM (PAK4), 15 μM (AKT1), 25 μM (ERK2), >50 μM (P38)^[1]

In Vitro: DB07268 (Compound 2b) also inhibits CHK1, PAK4, AKT1, and ERK2 with IC50s of 0.82 μM, 5.5 μM, 15 μM, and 25 μM, respectively^[1].