tcsc1450 Miriplatin (hydrate)

Miriplatin hydrate is a chemotherapy agent which belongs to the class of alkylating agents.

In Vitro: Miriplatin suspended in lipiodol (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis^[2].

In Vivo: Miriplatin (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells^[1]. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells^[2].