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Product Description
Miriplatin hydrate is a chemotherapy agent which belongs to the class of alkylating agents.
In Vitro: Miriplatin suspended in lipiodol (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis[2].
In Vivo: Miriplatin (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells[1]. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells[2].
Information
CAS No250159-48-9
FormulaC34H70N2O5Pt
Clinical Informationclinicalinformation
PathwayCell Cycle/DNA Damage
TargetDNA Alkylator/Crosslinker
Specifications
Purity / Grade>98%
Solubility10 mM in DMSO
Smilessmiles
Misc Information
Observed Molecular Weight782.01
related data
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