tcsc1059 Fostemsavir

Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4⁺ T cells.

IC50 & Target: HIV-1^[1]

In Vivo: Fostemsavir (BMS-663068) has good antiviral activity in subjects infected with virus shown to be susceptible (IC₅₀, <100 nM) to the agent^[1].