tcsc0887 Loratadine

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Product Description

Loratadine(SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.

IC50 value: 32 uM

Target: H1-receptor

Loratadine is a non-sedative antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells.

Information

CAS No79794-75-5
FormulaC22H23ClN2O2
Clinical Informationclinicalinformation
PathwayImmunology/Inflammation
GPCR/G Protein
TargetHistamine Receptor
Histamine Receptor

Specifications

Purity / Grade>98%
SolubilityDMSO : 50 mg/mL (130.59 mM; Need ultrasonic)
Smilessmiles

Misc Information

Alternative NamesSCH 29851;Loratidine
Observed Molecular Weight382.88
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