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BioChemicals
Nepicastat
tcsc0515
Nepicastat
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AVAILABLE SIZES
5mg
10mg
50mg
$
260.00
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ORDERING INFORMATION
International
TAICLONE BIOTECH CORP.
order@taiclone.com
+886-2-2735-9682
+886-2-2735-9807
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Product Description
Nepicastat (SYN117; RS-25560-197) is a dopamine beta-hydroxylase inhibitor with IC50 of 8.5 ± 0.8 and 9.0 ± 0.8 nM for bovine and human, respectively.
IC50 value: 8.5/9.0 nM(bovine/human dopamine beta-hydroxylase)
Dopamine beta-hydroxylase is an enzyme that catalyzes the conversion of dopamine to norepinephrine. Nepicastat (SYN117; RS-25560-197) has been studied as a possible treatment for congestive heart failure, and appears to be well tolerated as such.
Information
CAS No
173997-05-2
Formula
C
14
H
15
F
2
N
3
S
Clinical Information
clinicalinformation
Pathway
Metabolic Enzyme/Protease
Target
Dopamine β-hydroxylase
Specifications
Purity / Grade
>98%
Solubility
DMSO : ≥ 48 mg/mL (162.52 mM)
Smiles
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Misc Information
Alternative Names
SYN117;RS-25560-197
Observed Molecular Weight
295.35
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