tcsc0446 SD 0006

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Product Description

SD 0006 (SD-06) is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po).

IC50 & Target: IC50: 170 nM (p38MAPK).

Information

CAS No271576-80-8
FormulaC20H20ClN5O2
Clinical Informationclinicalinformation
PathwayMAPK/ERK Pathway
Targetp38 MAPK

Specifications

Purity / Grade>98%
SolubilityDMSO : ≥ 29 mg/mL (72.89 mM)
Smilessmiles

Misc Information

Alternative NamesSD-06
Observed Molecular Weight397.86
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