tcsc0042225 Salsolidine

Salsolidine is a tetrahydroisoquinoline alkaloid, acts as a stereoselective competitive MAO A inhibitor.

IC50 & Target: MAO A^[1]

In Vitro: Salsolidine is a tetrahydroisoquinoline alkaloid, acts as a stereoselective competitive MAO A inhibitor. The R-salsolidine is more active against MAO A than S-salsolidine (Ki, 6 μM and 186 μM)^[1]. Salsolidine weakly inhibits the binding of δ-receptor, with a K_i of >100 μM^[2]. Salsolidine has the potential of inhibiting Acetylcholinestearse and butyrylcholinesterase^[3].