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BioChemicals
E-7386
tcsc0040308
E-7386
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AVAILABLE SIZES
1mg
5mg
10mg
50mg
$
157.00
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ORDERING INFORMATION
International
TAICLONE BIOTECH CORP.
order@taiclone.com
+886-2-2735-9682
+886-2-2735-9807
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Western blot (WB)
Immunohistochemistry (IHC)
Immunofluorescence (IF)
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RNA Binding Protein Immunoprecipitation (RIP)
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Product Description
E-7386 is an orally active
CBP/beta-catenin
modulator.
IC50 & Target: CBP/beta-catenin
[1]
In Vivo:
E-7386 is an orally active CBP/beta-catenin modulator which can induce T cells infiltration into tumor and enhance antitumor activity of anti-PD-1 mAb in Wnt1 tumor syngeneic mice model. E-7386 shows significant antitumor activity in Wnt1 model. Infiltration of T cells is limited in vehicle control group, but T cell infiltration into tumors is clearly observed in E-7386 treatment group
[1]
.
Information
CAS No
1799824-08-0
Formula
C
39
H
48
FN
9
O
4
Clinical Information
clinicalinformation
Pathway
Epigenetics
Target
Epigenetic Reader Domain
Specifications
Purity / Grade
>98%
Solubility
10 mM in DMSO
Smiles
smiles
Misc Information
Observed Molecular Weight
725.85
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