tcsc0039396 Nemorexant

Nemorexant (ACT-541468) is a potent orexin receptor antagonist extracted from patent WO2015083094A1, compound example 7, has IC₅₀s of 2 nM and 3 nM for Ox₁ receptor and Ox₂ receptor, respectively.

IC50 & Target: IC50: 2 nM (Ox₁ receptor ), 3 nM (Ox₂ receptor)^[1]

In Vitro: Nemorexant (Compound example 7) is a orexin receptor antagonist with IC₅₀s of 2 nM and 3 nM for Ox₁ receptor and Ox₂ receptor, respectively^[1].