tcsc0039281 Seclidemstat

Seclidemstat (SP-2577) is a potent LSD1 inhibitor, with a mean IC₅₀ of 127 nM.

IC50 & Target: IC50: 127 nM (LSD1)^[1]

In Vivo: Seclidemstat (Compound 2577) reduces tumor volume at 40, 80 mg/kg by i.p. and also shows such effect at 80 mg/kg via p.o. dosing.