tcsc0035391 DPBQ

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Product Description

DPBQ is a p53 activator.

IC50 & Target: p53[1]

In Vitro: DPBQ elicits apoptosis and cell death and is selective for effects in 4N cells. DPBQ elicits expression and phosphorylation of p53 and this effect is specific to tetraploid cells. Knockdown of TP53 restores proliferation of tetraploid cells in the presence of DPBQ[1].

Information

CAS No7029-89-2
FormulaC24H14N2O2
Clinical Informationclinicalinformation
PathwayApoptosis
TargetMDM-2/p53

Specifications

Purity / Grade>98%
Solubility10 mM in DMSO
Smilessmiles

Misc Information

Observed Molecular Weight362.38
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