tcsc0031111 HIV-1 integrase inhibitor 3

HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC₅₀ of 2.7 nM.

IC50 & Target: IC50: 2.7 nM (INST)^[1]

In Vitro: HIV-1 integrase inhibitor 3 (compound 4c) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC₅₀ of 2.7 nM. HIV-1 integrase inhibitor 3 also displays an antiviral inhibitory potency against the Q148H/G140S mutant with an EC₅₀ of 7 nM^[1].