tcsc0024 CGP60474

CGP60474 is a potent VEGFR-2 inhibitor, with an IC₅₀ of 84 nM, and also an ATP-competitive PKC inhibitor.

IC50 & Target: IC50: 84 nM (VEGFR-2)^[1]


PKC^[2]

In Vitro: CGP60474 (Compound A) is a potent VEGFR-2 inhibitor, with an IC₅₀ of 84 nM^[1]. CGP60474 is also a PKC inhibitor, with competitive kinetics relative to ATP^[2].