tcsc0020905 (-) -PX20606 trans isomer

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Product Description

(-)-PX20606 trans isomer is a FXR agonist with EC50s of 18 and 29 nM for FXR in FRET and M1H assay, respectively.

IC50 & Target: EC50: 18 nM (FXR in FRET assay), 29 nM (FXR in M1H assay)[1]

Information

CAS No1268244-88-7
FormulaC29H22Cl3NO4
Clinical Informationclinicalinformation
PathwayMetabolic Enzyme/Protease
TargetFXR

Specifications

Purity / Grade>98%
Solubility10 mM in DMSO
Smilessmiles

Misc Information

Alternative Names(-)-PX-102 trans isomer;(-)-PX-104
Observed Molecular Weight554.85
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