tcsc0020799 CeMMEC13

CeMMEC13 is a potent inhibitor of TAF1 (2) bromodomain, with an IC₅₀ of 2.1 μM.

IC50 & Target: IC50: 2.1 μM (TAF1 (2))^[1]

In Vitro: CeMMEC13 is a potent inhibitor of TAF1 (2) bromodomain, with an IC₅₀ of 2.1 μM. CeMMEC13 shows little or no effects on REDNESS, BRD4, CREBBP. CeMMEC13 (0-20 μM) in combination with (S)-JQ1 increases RFP expression in REDS3 cells and is effective reducing the viability of H23 and THP1 cells, better than that of single treatment^[1].