tcsc0020453 7-Chloro-4-hydroxyquinoline-2-carboxylic acid

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Product Description

7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex and also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM.

IC50 & Target: N-methyl-D-aspartate receptor[1]


Ki: 0.59 μM (reuptake of glutamate)[1]

Information

CAS No18000-24-3
FormulaC10H6ClNO3
Clinical Informationclinicalinformation
PathwayMembrane Transporter/Ion Channel
Neuronal Signaling
TargetiGluR
iGluR

Specifications

Purity / Grade>98%
SolubilityDMSO : 30 mg/mL (134.16 mM; Need ultrasonic and warming)
Smilessmiles

Misc Information

Alternative Names7-Chlorokynurenic acid
Observed Molecular Weight223.61
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