tcsc0018484 PF-02575799

PF-02575799 is a microsomal triglyceride transfer protein (MTP) inhibitor with an IC₅₀ of 0.77±0.29 nM.

IC50 & Target: IC50: 0.77±0.29 nM (MTP)^[1]

In Vitro: PF-02575799 is compound 13 from the reference^[1].

In Vivo: PF-02575799 produces appreciable triglyceride effects at its minimally effective dose (10 mg/kg). PF-02575799 significant increase alanine transaminase at 100 mg/kg^[1].