tcsc0018177 BACE1-IN-1

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Data sheet

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Product Description

BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.

IC50 & Target: IC50: 32 nM (human BACE1), 47 nM (human BACE2)[1]

Information

CAS No1310347-50-2
FormulaC18H14F3N5O2
Clinical Informationclinicalinformation
PathwayNeuronal Signaling
TargetBeta-secretase

Specifications

Purity / Grade>98%
Solubility10 mM in DMSO
Smilessmiles

Misc Information

Observed Molecular Weight389.33
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