tcsc0018101 Bevenopran

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Product Description

Bevenopran is a peripheral μ-opioid receptor antagonist.

IC50 & Target: μ-opioid receptor[1]

In Vivo: Bevenopran is a peripheral μ-opioid receptor antagonist. Bevenopran is currently under investigation for the treatment of opioid-induced bowel dysfunction (OBD)[1]. Bevenopran tends to increase bowel movement (BM) frequency, especially for 0.1 mg twice daily and 4 mg daily, respectively[1].

Information

CAS No676500-67-7
FormulaC20H26N4O4
Clinical Informationclinicalinformation
PathwayGPCR/G Protein
Neuronal Signaling
TargetOpioid Receptor
Opioid Receptor

Specifications

Purity / Grade>98%
Solubility10 mM in DMSO
Smilessmiles

Misc Information

Alternative NamesCB-5945;ADL-5945
Observed Molecular Weight386.44
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