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BioChemicals
BAY-598
tcsc0015642
BAY-598
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AVAILABLE SIZES
1mg
5mg
$
171.00
Add to Cart
ORDERING INFORMATION
International
TAICLONE BIOTECH CORP.
order@taiclone.com
+886-2-2735-9682
+886-2-2735-9807
Data sheet
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Western blot (WB)
Immunohistochemistry (IHC)
Immunofluorescence (IF)
Immunocytochemistry (ICC)
Immunoprecipitation (IP)
Co-Immunoprecipitation (CoIP)
Chromatin Immunoprecipitation (ChIP)
RNA Binding Protein Immunoprecipitation (RIP)
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UG
CELLS
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Product Description
BAY-598 is selective small molecule inhibitor of
SMYD2
.
IC50 & Target: SMYD2
[1]
In Vitro:
BAY-598 treatment blocks
in vitro
methylation of MAPKAPK3 by SMYD2 but has no activity against the SMYD2-related KMT SMYD3. BAY-598 treatment reduces the growth of
Kras;p53
mutant PDAC cells after 9 d in culture but has little impact on the growth of
Kras;p53;Smyd2
mutant cells
[1]
.
Information
CAS No
1906919-67-2
Formula
C
22
H
20
Cl
2
F
2
N
6
O
3
Clinical Information
clinicalinformation
Pathway
Epigenetics
Target
Histone Methyltransferase
Specifications
Purity / Grade
>98%
Solubility
10 mM in DMSO
Smiles
smiles
Misc Information
Observed Molecular Weight
525.34
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