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BioChemicals
Tectorigenin
tcsc0009804
Tectorigenin
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5mg
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50mg
$
100.00
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ORDERING INFORMATION
International
TAICLONE BIOTECH CORP.
order@taiclone.com
+886-2-2735-9682
+886-2-2735-9807
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Product Description
Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of
Pueraria thomsonii
Benth.
In Vitro:
Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of
Pueraria thomsonii
Benth. Palmitic acid (PA)-stimulated ROS production is abolished by treatment with Tectorigenin for HUVECs in a dose-dependent manner (0.1, 1, 10 μM). Treatment with Tectorigenin attenuates enhanced IKKβ phosphorylation and effectively blocks NF-κB activation by inhibition of p65 phosphorylation at concentrations ranging from 0.1 to 10 μM. Tectorigenin treatment also effectively inhibits PA-augmented TNF-α and IL-6 production in a concentration dependent manner
[1]
. The number of viable HepG2 cells treated by Tectorigenin decreases in a concentration- and time-dependent manner. When HepG2 cells are treated with Tectorigenin at 5, 10 and 20 mg/L for 24 h, the viability rate is 91%, 79% and 62%, respectively
[2]
.
Information
CAS No
548-77-6
Formula
C
16
H
12
O
6
Clinical Information
clinicalinformation
Pathway
Others
Target
Others
Specifications
Purity / Grade
>98%
Solubility
DMSO : 150 mg/mL (499.57 mM; Need ultrasonic and warming)
Smiles
smiles
Misc Information
Observed Molecular Weight
300.26
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