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BioChemicals
TS-011
tcsc0007825
TS-011
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AVAILABLE SIZES
1mg
5mg
10mg
$
1,073.00
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ORDERING INFORMATION
International
TAICLONE BIOTECH CORP.
order@taiclone.com
+886-2-2735-9682
+886-2-2735-9807
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Product Description
TS-011 is a selective inhibitor of
20-Hydroxyeicosatetraenoic acid
synthesis.
In Vivo:
TS-011 is a selective inhibitor of 20-Hydroxyeicosatetraenoic acidsynthesis. TS-011 at a dose of 0.3 mg/kg inhibits the reduction in the blood flow velocities at 1 and 7 h after reperfusion (P<0.001). In addition, TS-011 inhibits the increase in the blood flow velocity at 24 h after reperfusion (P<0.01). TS-011 protects the microvascular perfusion area from the loss observed in vehicle-treated mice. TS-011, at a dose of 0.3 mg/kg, also reduces the infarct volume by almost 40% (P<0.05)
[1]
. In 9 dogs with delayed vasospasm, acute blockade of the synthesis of 20-HETE with TS-011 (1 mg/kg IV) significantly increases the diameter of the basilar artery by 39%
[2]
.
Information
CAS No
339071-18-0
Formula
C
11
H
14
ClN
3
O
2
Clinical Information
clinicalinformation
Pathway
Others
Target
Others
Specifications
Purity / Grade
>98%
Solubility
10 mM in DMSO
Smiles
smiles
Misc Information
Observed Molecular Weight
255.7
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