tcsa17095 Anti HSPB8 Antibody

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Product Description

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Information

ApplicationWB, IHC, IF
Species ReactivityHuman, Mouse, Rat
Host SpeciesRabbit
Immunogen / Amino acidsRecombinant protein of human HSPB8
ConjugationUnconjugated
ClonalityPolyclonal
IsotypeIgG

Specifications

FormLiquid
Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:100

Misc Information

Storage InstructionStore at -20C. Avoid freeze / thaw cycles.
Alternative NamesHSPB8 antibody
Heat shock protein beta-8 antibody
HspB8 antibody
Alpha-crystallin C chain antibody
E2-induced gene 1 protein antibody
Protein kinase H11 antibody
Small stress protein-like protein HSP22 antibody
HSPB8 antibody
SwissProtQ9UJY1
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