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BioChemicals
Elagolix sodium
Elagolix sodium
100mg
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AVAILABLE SIZES
c32h29f5n3nao5
$
10.00
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ORDERING INFORMATION
International
TAICLONE BIOTECH CORP.
order@taiclone.com
+886-2-2735-9682
+886-2-2735-9807
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Product Description
No product descriptions available. Please refer to the product information & specifications for details.
Information
CAS No
casno
Formula
832720
-
36
-
2
Clinical Information
clinicalinformation
Pathway
GNRH Receptor
Target
Elagolix sodium is a human
GnRH receptor
(
GnRHR
) antagonist with an
IC
50
and
K
i
of 0.25 and 3.7 nM, respectively. IC50 & Target: IC50: 0.25 nM (GnRHR)
[1]
Ki: 3.7 nM (GnRHR)
[2]
In Vitro:
Elagolix sodium is a human GnRH receptor (GnRHR) antagonist with an IC
50
of 0.25 nM in Kinase assay. Elagolix sodium has advanced to phase 3 trials for the treatment of endometriosis and uterine fibroids. Elagolix sodium also shows NFAT inhibition with an IC
50
of 5.4 nM and effectively blocks Ca
2+
flux with an IC
50
of 0.86 nM
[1]
. Kinase assay also demonstrates that Elagolix sodium is a human GnRH receptor (GnRHR) antagonist with a K
i
value of 3.7 nM
[2]
.
Specifications
Purity / Grade
653.57
Solubility
Phase 3
Smiles
smiles
Misc Information
Alternative Names
780
Observed Molecular Weight
NBI-56418 sodium
related data
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