tcel169 NCI-N87 [N87]

NCI-N87 cells express the surface glycoproteins carcinoembryonic antigen(CEA) and TAG 72, and are L-dopa decarboxylase(DDC) negative. They were minimally positive for vasoactive intestinal peptide(VIP) receptors and lacked gastrin receptors. They were found to express receptors for muscarinic cholinergic agents. No evidence of amplification or rearrangements was noted with the N-myc, L-myc, myb and EGF receptor genes. The cell line expressed levels of c-myc and c-erb-B 2 RNA that were comparable to other cell lines.There was no expression of the following genes: N-myc, L-myc, c-cis, IGF-2, or gastrin releasing peptide. NCI-N87 cells have a reported plating efficiency of 4.3%.