Product Description
This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.
Information
ApplicationWB
Research AreaCancer, Signal transduction
Species ReactivityHuman, Mouse
Host SpeciesRabbit
Immunogen / Amino acidsRecombinant protein of human PDE6D
ConjugationUnconjugated
ClonalityPolyclonal
IsotypeIgG
Specifications
FormLiquid
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration1mg/ml
Recommended DilutionWB 1:500 - 1:2000
Misc Information
Storage InstructionStore at -20℃. Avoid freeze / thaw cycles.
Alternative Names5''-cyclic phosphodiesterase subunit delta,GMP PDE delta,GMP-PDE delta,p17 protein,PDE 6,PDE 6D,PDE D,PDE6,PDE6D,PDE6D,PDED,Phosphodiesterase 6D cGMP specific,Phosphodiesterase 6D cGMP specific rod delta,Protein p17,Retinal rod photoreceptor cGMP phosphodiesterase delta,Retinal rod rhodopsin sensitive cGMP 3' 5' cyclic phosphodiesterase subunit delta,Retinal rod rhodopsin-sensitive cGMP 3''