Product Description
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
Information
ApplicationWB, IHC, IF, IP
Research AreaCancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem cells
Species ReactivityHuman, Mouse, Rat, Monkey
Host SpeciesRabbit
Immunogen / Amino acidsA synthetic peptide of human HDAC2
ConjugationUnconjugated
ClonalityPolyclonal
IsotypeIgG
Specifications
FormLiquid
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration1mg/ml
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:50 - 1:200
Misc Information
Storage InstructionStore at -20℃. Avoid freeze / thaw cycles.
Alternative NamesD10Wsu179e,HD 2,HD2,HDAC 2,Hdac2,HDAC2,Histone deacetylase 2 (HD2),Histone deacetylase 2,OTTHUMP00000017046,OTTHUMP00000227077,OTTHUMP00000227078,RPD3,transcriptional regulator homolog RPD3,YAF1,YY1 associated factor 1,YY1 transcription factor binding protein,Yy1bp