tcna10740saf AKR1B1 Antibody / Aldose reductase- sodium azide free

IHC testing of FFPE human prostate cancer with AKR1B1 antibody (clone ADRD1-1). Required HIER: boil tissue sections in 10mM citrate buffer, pH6, for 10-20 min followed by cooling at RT for 20 min.
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$595.00 ORDERING INFORMATION International
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Data sheet

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Product Description

The AKR1B1 gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [RefSeq]

Information

ApplicationIHC-P, WB
Species ReactivityHuman. Other species not tested.
Host SpeciesMouse
Immunogen / Amino acidsRecombinant protein was used as the immunogen for this AKR1B1 antibody.
ClonalityMonoclonal (mouse origin)
ClonesADRD1-1
IsotypeMouse IgG1, kappa

Specifications

Storage Buffer1 mg/ml in 1X PBS; sodium azide free
Recommended DilutionWestern blot: 0.5-1ug/ml
Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT
Prediluted IHC only format: incubate for 30 min at RT (1)

Misc Information

Storage InstructionStore the AKR1B1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
SwissProtP15121
ReferencesProtein G affinity chromatography
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