tcna5081 Connexin 43 Antibody / Cx43

Data sheet

Download PDF Datasheet

Technical Inquries

Submit Review

Product Description

Connexin 43 (Cx43), also called GAP Junction Protein, alpha, is a member of the connexin gene family and is abundantly expressed in the heart and liver. Connexin 43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Cx43 also plays a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph.

Information

ApplicationWB, IHC-P, IHC-F, ICC
Species ReactivityHuman, Mouse, Rat
Host SpeciesRabbit
Immunogen / Amino acidsAmino acids 351-367 (HELQPLAIVDQRPSSRA-human) were used as the immunogen for this Cx43 antibody (100% conserved in mouse and rat).
ConjugationAntigen affinity purified
ClonalityPolyclonal
IsotypeRabbit IgG

Specifications

FormLyophilized powder
Storage Buffer0.5mg/ml if reconstituted with 0.2ml sterile DI water
Recommended DilutionWestern blot: 0.5-1ug/ml
IHC (Paraffin): 0.5-1ug/ml
IHC (Frozen): 0.5-1ug/ml
Immunocytochemistry: 0.5-1ug/mlTitration of the Cx43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Misc Information

Storage InstructionThe lyophilized Cx43 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing.
SwissProtP17302
ReferencesAntigen affinity purified
Get valuable resources and offers directly to your email.