tcna1383pre Tyrosinase-Related Protein-1 / TRP1 Antibody- prediluted

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Product Description

Tyrosinase-Related Protein-1 / TYRP1 / TRP1 is involved in melanin synthesis. It is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. It is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Information

ApplicationIHC-P
Species ReactivityHuman. Other species not known.
Host SpeciesRabbit
Immunogen / Amino acidsA portion of amino acids 257-377 was used as the immunogen for this recombinant TRP1 antibody.
ConjugationUnconjugated
ClonalityRecombinant Rabbit Monoclonal
ClonesTYRP1/2340R
IsotypeRabbit IgG, kappa

Specifications

FormLiquid
Storage BufferPrediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Recommended DilutionPrediluted IHC only format : incubate for 30 min at RT (1)The optimal dilution of the recombinant TRP1 antibody for each application should be determined by the researcher.

Misc Information

Storage InstructionStore the recombinant TRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
SwissProtP17643
ReferencesProtein A affinity chromatography
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