Product Description
This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified.
Information
Research AreaNeuroscience, Cardiovascular,
Species ReactivityHuman, Mouse, Rat
Host SpeciesRabbit
IsotypeIgG
Specifications
FormLiquid
Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Tested ApplicationWB, IHC
Recommended DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
Misc Information
Storage InstructionStore at -20℃. Avoid freeze / thaw cycles.
Alternative NamesKCNH2; ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1
Calculated Molecular Weight60kDa/90kDa/97kDa/115kDa/121kDa/126kDa
Observed Molecular Weight148kDa
PurificationAffinity purification
Positive Control293T, SH-SY5Y, SW620, MCF7, K-562, Mouse brain
Cellular LocationCell membrane, Multi-pass membrane protein