Product Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.
Information
ApplicationWB, IHC, IF, IP
Research AreaCancer, MAPK pathway, MAPK/p38 pathway, MAPK/ERK pathway,
Species ReactivityHuman, Mouse, Rat, Other (Wide Range)
Host SpeciesRabbit
IsotypeIgG
Specifications
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:200
Misc Information
Storage InstructionStore at -20℃. Avoid freeze / thaw cycles.
Alternative NamesH3/j;H3FJ
Calculated Molecular Weight15kDa
PurificationAffinity purification
Cellular LocationChromosome,Nucleus,