tcba6856 XRCC4 Polyclonal Antibody

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Product Description

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.

Information

ApplicationWB, IHC, IF
Research AreaCancer, Apoptosis, DNA Damage/Repair,
Species ReactivityHuman, Mouse, Rat
Host SpeciesRabbit
IsotypeIgG

Specifications

FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:10 - 1:100

Misc Information

Storage InstructionStore at -20℃. Avoid freeze / thaw cycles.
Alternative NamesSSMED
SwissProtQ13426
Gene ID7518 (human);
Calculated Molecular Weight35kDa/38kDa
PurificationAffinity purification
Cellular LocationNucleus,
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